Although the mission technically takes place in Karnaca Docks, it starts before that, when you are on board the Dreadful Wale ship and you are visited by the Outsider who grants you powers, should you choose to accept his gift.
After speaking with Meagan Foster on the Dreadful Wale, you decide that the best lead for tracking down the “Crown Killer” is the Addermire Institute, which can be reached by taking a carriage from the Addermire Station. Also, you must find out where Sokolov was taken.
There are multiple Dishonored 2 collectibles in Mission 2, and the new area supports many pathways towards the objective, which means you can easily overlook some of these items.
Moreover, there are a few that are locked behind puzzles, which are explained in the following guide.
The Dishonored 2 collectibles guide features information regarding all the collectibles in Mission 2.
Combine them with the screenshots or the YouTube video at the end of the guide and you should have no trouble in locating all Runes, Paintings, Bonecharms and Blueprints in this specific mission.
Mission 2 – Edge of the World Collectibles Locations
Outsider Shrine #1, Rune #1, #2
The first Outsider Shrine where you can get two Runes is unmissable. You find it at the end of the sequence with the Outsider, as part of a tutorial after you receive the Heart device.
Once you get on board the Dreadful Wale ship, head on the deck and use the Heart. On the left side of the ship, in the water, you can spot a Rune.
Jump in the water and swim to an old wreck to recover the collectible.
The next Dishonored 2 Mission 2 Rune can be found after you arrive in Karnaca.
When you start the mission head up the stairs and go left to the wharf. The Rune is inside a whale carcass, hard to miss.
From the dead whale, Blink/Far Reach on top of the store canopies to your right and go inside the building through the open window. Against a wall next to a desk is a safe.
Open it and retrieve the Blueprint that’s inside.
Head outside on the canopies and jump on the balcony to your left-hand side. Use your powers to reach a fan that’s hung up on the side of the building and from there jump onto another balcony.
Inside the room is the first Dishonored 2 Painting in Edge of the World.
Follow the road from the whale carcass to find the Black Market Shop – the door is latched from the other side the first time you visit the building. Buy the Rune from the merchant or steal a key from the infested building and rob the place.
Near the black market is a building that was infested by Bloodflies. Jump inside through the window where the body is and go to the second floor.
Destroy one of the nests on the floor to find the first Bonecharm collectible.
Next, go to the restricted area where the Wall of Light blocks your path. Use the stairs that are on the right-hand side and go to the second story of the building, inside the apartment with two Overseers.
Under a plank in the floor is another Dishonored 2 Mission 2 Bonecharm.
From the previous collectible, turn right and head inside the bathroom to find a Painting.
Outsider Shrine #2, Rune #6, #7
In the same bathroom, next to the Painting, is the second Outsider Shrine in the mission, which also contains two Dishonored 2 Runes.
Exit the bathroom and head back to the other side of the room. Access the balcony that overlooks the canal area either by opening the window or by breaking the door.
Use your powers to jump on the canopy to your right and then onto the roof. You can find the Bonecharm on the other side of the roof, on a mattress with a dead body (pay attention to the Bloodflies).
Jump down from the roof to street level. Head to the Overseer building and eliminate the enemies that are talking to the crowd outside.
On a small table, next to them, is a Bonecharm collectible, hard to miss.
On the same table with the Bone Charm is another Dishonored 2 Rune.
Use the front entrance or your Blink/Far Reach abilities to access the third floor of the Overseer Outpost. The Blueprint is on a desk inside an important Overseer’s office.
If you’re jumping on the balcony that’s exactly above the table with the previous two collectibles you bump into the said desk as you enter the office.
The third Painting in Mission 2 is hung on a wall across the desk with the Blueprint collectible.
The next Dishonored 2 Rune is inside a locked safe in the same office. However, to open the safe you have to find out the combination, which seems to be random.
Read the note on the table inside the room to your right (while facing the Painting) and remember the three Strictures written in the note.
Now go to the safe and read the book “The Seven Strictures” that is right next to it.
The Strictures are marked with numbers from 1 to 7, and the note you read earlier gives you the combination (check the mission clues in the pause menu if you’re having trouble).
Open the door near the safe and go to the upper floor. Steal the key from one of the Overseers in the room and unlock the interrogation room with the dead body inside (alternatively you can use the balconies to access the room).
Grab the Corrupted Bonecharm from the table before leaving.
Next, leave the Overseer building and jump down in the canal nearby. Go to the gate where the water pours into the canal and use the crossbow to shoot a plank that is blocking the flow. The final Dishonored 2 Mission 2 Rune will slide down toward you.
Follow the train tracks to Addermire Station and go to the Winslow Safe Company building across the street. The last Bonecharm in the Edge of the World mission is locked inside a safe under the staircase.
The problem is that the safe combination is random. To find it out, open the cash register and grab the Safe Contest Combination.
From the safe where you picked up the Bonecharm inside the Winslow building, go to the room at the back and grab the key from the desk.
Head through the back door (or use the alleyway between the buildings) and go all the way to the top to unlock Dr. Hypatia’s apartment.
There is a Painting in the main hallway, which is also the final collectible in Dishonored 2 Mission 2.